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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Postbulbar duodenal ulcer in a patient with pentagastrin-fast achlorhydria.

This report describes the clinicopathologic features of a 55-yr-old man found to have a bleeding, postbulbar duodenal ulcer and fasting hypergastrinemia. Gastric analysis revealed pentagastrin-fast achlorhydria. Healing of the ulcer was documented 8 wk after vagotomy, antrectomy, gastrojejunostomy, and a course of sucralfate therapy. The etiology of the postbulbar ulcer was uncertain. This is the first documented case of a duodenal ulcer with pentagastrin-fast achlorhydria.[1]


  1. Postbulbar duodenal ulcer in a patient with pentagastrin-fast achlorhydria. Goldschmiedt, M., Peterson, W.L., Vuitch, F., Feldman, M. Gastroenterology (1989) [Pubmed]
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