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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

Prevalence of mottled enamel in permanent dentition of children participating in a fluoride programme at the Amsterdam dental school.

The prevalence of mottled enamel in the permanent dentition of children participating a fluoride (F-) programme at the Amsterdam Dental School has been investigated in a pilot study, utilizing the Thylstrup-Fejerskov (TF) index. From all children examined (n = 83) 74% exhibited mottled enamel, in a slight to moderate degree. More teeth were affected and the degree of mottling was higher when children started to use F- at an earlier age. Unintentional ingestion of toothpaste containing 0.15% F- during frequent tooth brushing in combination with the daily intake of F- tablets before the age of four may explain the high prevalence of mottled enamel.[1]

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