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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Nourseothricin (streptothricin) inactivated by a plasmid pIE636 encoded acetyl transferase: nature of the inactivated nourseothricin.

Nourseothricin, a mixture of several streptothricins, is inactivated by an acetyl transferase produced by Escherichia coli containing the plasmid pIE636. Nourseothricin inactivated in the presence of 14C-acetate was purified and submitted to partial hydrolysis. In the hydrolysate besides others a radioactive and ninhydrin-reactive substance moving only slightly towards the cathode was found. It proved to be [14C]-acetyl beta-lysine.[1]

References

  1. Nourseothricin (streptothricin) inactivated by a plasmid pIE636 encoded acetyl transferase: nature of the inactivated nourseothricin. Seltmann, G., Beer, W. Acta Microbiol. Hung. (1987) [Pubmed]
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