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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Mapping of the bcl-2 oncogene on mouse chromosome 1.

Two bcl-2 alleles have been identified in inbred strains of mice by restriction fragment length polymorphism (RFLP). Analysis of a bcl-2 RFLP in a series of bilineal congenic strains (C.D2), developed as a tool for chromosomal mapping studies, revealed linkage of bcl-2 to the Idh-1/Pep-3 region of murine chromosome 1. The co-segregation of bcl-2 alleles with allelic forms of two other chromosome 1 loci, Ren-1,2 and Spna-1, in a set of back-cross progeny, positions bcl-2 7.8 cM centromeric from Ren-1,2.[1]


  1. Mapping of the bcl-2 oncogene on mouse chromosome 1. Mock, B.A., Givol, D., D'Hoostelaere, L.A., Huppi, K., Seldin, M.F., Gurfinkel, N., Unger, T., Potter, M., Mushinski, J.F. Cytogenet. Cell Genet. (1988) [Pubmed]
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