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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Molecular analysis of the locus elav in Drosophila melanogaster: a gene whose embryonic expression is neural specific.

The embryonic lethal abnormal visual system (elav) locus in Drosophila melanogaster, a vital gene mapping within the 1B5-1B9 region of the X-chromosome has been cloned and analysed. Previous developmental analyses have shown that in addition to the embryonic requirement there is a post-embryonic requirement for elav function in the cells of the visual system. A DNA segment containing elav+ function was defined through germ line transformation experiments. This region encodes three embryonic poly(A)+ RNAs and two adult transcripts which are preferentially expressed in the head. In situ hybridization experiments clearly demonstrate that the embryonic expression of elav is restricted to the nervous system.[1]

References

  1. Molecular analysis of the locus elav in Drosophila melanogaster: a gene whose embryonic expression is neural specific. Campos, A.R., Rosen, D.R., Robinow, S.N., White, K. EMBO J. (1987) [Pubmed]
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