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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Sodium aurothiomalate does not block interleukin 1 production in rabbits.

Gold salts may attenuate inflammatory processes by inhibiting interleukin 1 production. It is shown that sodium aurothiomalate does not act as an antipyretic after intravenous injection of two pyrogens into rabbits. Consequently, it cannot suppress interleukin 1 production, a conclusion confirmed by an in vitro lymphocyte activating factor assay. Chronic sodium aurothiomalate treatment, however, did depress the blood leucocyte count significantly.[1]


  1. Sodium aurothiomalate does not block interleukin 1 production in rabbits. Zurovsky, Y., Laburn, H.P., Mitchell, D., Ruck, A. Ann. Rheum. Dis. (1988) [Pubmed]
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