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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Late onset isofenphos neurotoxicity.

Late progressive polyneuropathy followed by pyramidal findings in a 20 year old agricultural labourer who ingested Isofenphos solution during his work, is presented. The patient was confined to a wheelchair within 6 weeks, regained walking ability within 6 months, and a 23 months' follow up revealed slight additional clinical improvement with minimal progression of the pyramidal signs. The neuropathic clinical manifestations, the EMG and the nerve conduction studies were compatible with a pathology of a distal, mainly axonal, mainly motor neuropathy.[1]


  1. Late onset isofenphos neurotoxicity. Catz, A., Chen, B., Jutrin, I., Mendelson, L. J. Neurol. Neurosurg. Psychiatr. (1988) [Pubmed]
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