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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Diffusing lung capacity and cyclosporine in patients with heart transplants.

Pulmonary function studies were performed in 10 patients undergoing surgery for heart transplantation. The study was repeated 6 to 12 months after surgery. The comparison between data before and after transplantation showed an overall improvement in lung function indices, except for the lung diffusing capacity (DLCO). A mean 14% reduction (p less than 0.01) of DLCO was observed. In the absence of evidence of other lung disease or rejection reaction in these patients, this finding may be related to a side effect of cyclosporine on the lung and deserves further investigation.[1]

References

  1. Diffusing lung capacity and cyclosporine in patients with heart transplants. Casan, P., Sanchis, J., Cladellas, M., Amengual, M.J., Caralps, J.M. The Journal of heart transplantation. (1987) [Pubmed]
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