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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Intranasal chalcone, Ro 09-0410, as prophylaxis against rhinovirus infection in human volunteers.

The antirhinovirus agent chalcone Ro 09-0410 was tested in double-blind place-controlled volunteer trials for its protective efficacy against experimental rhinovirus infection. Fifty volunteers received either drug (26 volunteers) or placebo (24 volunteers) both before and after challenge with 20-40 tissue culture infecting dose (TCID50) of human rhinovirus 2 (RV2). There was no evidence that medication significantly reduced the incidence of infection or illness, indeed there was some increase in the nasal secretion produced.[1]

References

  1. Intranasal chalcone, Ro 09-0410, as prophylaxis against rhinovirus infection in human volunteers. Al-Nakib, W., Higgins, P.G., Barrow, I., Tyrrell, D.A., Lenox-Smith, I., Ishitsuka, H. J. Antimicrob. Chemother. (1987) [Pubmed]
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