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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Methylphenidate in hyperkinetic children: differences in dose effects on learning and social behavior.

Methylphenidate (Ritalin) is widely prescribed for hyperkinetic children. This study showed a peak enchancement of learning in children after being given a dose of 0.3 milligram per kilogram of body weight, and a decrement in learning in those given larger doses; social behavior showed the most improvement in children given 1.0 milligram per kilogram. These results had been hypothesized from theoretical dose-response curves which indicate different target behaviors would improve at different doses.[1]

References

  1. Methylphenidate in hyperkinetic children: differences in dose effects on learning and social behavior. Sprague, R.L., Sleator, E.K. Science (1977) [Pubmed]
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