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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Pseudomembranous colitis associated with antibiotic prophylaxis in orthopaedic surgery.

We report 16 orthopaedic patients who had antibiotic-associated diarrhoea (pseudomembranous colitis) after operation. There was an association with the use of cephradine and with the prolongation of prophylaxis for more than three peri-operative doses. Five cases occurred as a cluster, suggesting that the causative agent, Clostridium difficile, may be infectious in some situations.[1]

References

  1. Pseudomembranous colitis associated with antibiotic prophylaxis in orthopaedic surgery. Cannon, S.R., Dyson, P.H., Sanderson, P.J. The Journal of bone and joint surgery. British volume. (1988) [Pubmed]
 
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