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Assignment of the gene for carboxypeptidase A to human chromosome 7q22----qter and to mouse chromosome 6.

A rat cDNA probe for preprocarboxypeptidase A was used to follow the segregation of the human gene for carboxypeptidase A ( CPA) in 49 human X mouse somatic cell hybrids using Southern filter hybridization techniques. CPA was assigned to human chromosome 7q22----qter. Similarly, the probe was used to follow the segregation of the mouse gene for carboxypeptidase A (Cpa) in 19 mouse X Chinese hamster somatic cell hybrids. Cpa was assigned to mouse chromosome 6. The gene for carboxypeptidase A forms part of a syntenic group that is conserved in man and mouse.[1]

References

  1. Assignment of the gene for carboxypeptidase A to human chromosome 7q22----qter and to mouse chromosome 6. Honey, N.K., Sakaguchi, A.Y., Lalley, P.A., Quinto, C., Rutter, W.J., Naylor, S.L. Hum. Genet. (1986) [Pubmed]
 
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