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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Androstenedione may organize or activate sex-reversed traits in female spotted hyenas.

Spotted hyenas (Crocuta crocuta Erxleben) present a unique syndrome of reversal in behavioral and anatomical distinction between the sexes: females are heavier and more aggressive than males and dominant over them. The female's external genitalia include a false scrotum and a fully erectile pseudopenis through which mating and birth take place. Results of studies of circulating testosterone levels in wild spotted hyenas do not account for the "male-like" characteristics of the female. Androstenedione, however, is consistently higher in females than in males, particularly during early infancy. Experiments on rodents show that androstenedione can be a potent organizer of anatomical and behavioral differentiation. This study suggests that it may also produce the profound virilization of female spotted hyenas.[1]

References

  1. Androstenedione may organize or activate sex-reversed traits in female spotted hyenas. Glickman, S.E., Frank, L.G., Davidson, J.M., Smith, E.R., Siiteri, P.K. Proc. Natl. Acad. Sci. U.S.A. (1987) [Pubmed]
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