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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Panniculitis in familial Mediterranean fever. Case report with histopathologic findings.

A 79-year-old Armenian-born woman with stable, long-term familial Mediterranean fever had progression of chronic renal failure concurrently with two types of skin lesions. One lesion resembled erysipelas, which is quite common in familial Mediterranean fever, whereas the other was panniculitis, only occasionally described in familial Mediterranean fever. The unique histopathologic features of the latter are presented. The onset of acute cutaneous disease in this patient coincided with worsening renal disease and preceded a flare of disease activity in other sites after a 14-year period of quiescence. The severe and unremitting pain from the skin lesions and their tendency to form nonhealing ulcers were substantial causes of morbidity in this patient with familial Mediterranean fever.[1]


  1. Panniculitis in familial Mediterranean fever. Case report with histopathologic findings. Danar, D.A., Kwan, T.H., Stern, R.S., Kasdon, E.J., Birnbaum, P.S., Brown, R.S. Am. J. Med. (1987) [Pubmed]
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