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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 

The rat MIS1/ Pvt-1 locus is syntenic with MYC on chromosome 7.

Mouse Pvt-1 and rat MIS1 are frequent proviral integration sites in retrovirally induced lymphomas. The Pvt-1 locus is also involved in mouse plasmacytoma (6;15) and in the variant Burkitt lymphoma (2;8) translocations. We show that the Pvt-1/MIS1 locus is syntenic with MYC on rat chromosome 7. This is consistent with a postulate of close linkage and, possibly, a functional relationship between the MYC protooncogene and the MIS1/ Pvt-1 locus.[1]

References

  1. The rat MIS1/Pvt-1 locus is syntenic with MYC on chromosome 7. Ingvarsson, S., Wirschubsky, Z., Szpirer, J., Levan, G., Klein, G., Sümegi, J. Cytogenet. Cell Genet. (1987) [Pubmed]
 
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