The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Genetic analysis of febrile convulsions: twin and family studies.

Thirty-two twin pairs and 673 sibship-cases with febrile convulsions ( FC) were studied. Twin study: The pairwise concordance rate for FC was 56% (10/18 pairs) in monozygotic and 14% (2/14 pairs) in dizygotic twins (P less than 0.05). Intra-pair similarity of clinical symptoms in concordant twin pairs was greater than that in sibship-cases. Sibship-pair study (population): In sibship-pair study a large positive correlation of some clinical symptoms - in particular, age at onset of FC, exogenous factors, and degree of fever (P less than 0.001 for each) - was indicated. Compared with FC children with no family history, those with such family history had a higher frequency of age at onset between 8 and 19 months, exogenous factors, low degree of fever before onset of convulsions, many recurrences, and recurrence after age 3 (P less than 0.01-0.001 for each). Morbidity risk among near relatives was highest in first-degree relatives (16%) than in second (4.0%) or third-degree relatives (4.1%). The following differences were found: siblings (24%) greater than parents (12%), uncles (4.5%) greater than aunts (3.5%), male cousins (4.4%) greater than female cousins (3.8%). Segregation ratio, influence by affection of father or mother, and maternal preponderance were analysed. Similar findings were also observed in the clinic study. A multifactorial mode of inheritance for FC receives some support from this study, and the heritability was estimated to be 75% in the population study. The results may be useful for genetic counselling for FC.[1]

References

 
WikiGenes - Universities