The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

FEB1  -  febrile convulsions 1

Homo sapiens

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of FEB1

  • RESULTS: We report the exclusion of the FC trait in our families to FEB1 on 8q13-21 and to a second febrile convulsion locus on 19p13 [1].
  • We report a clinical and genetic study of a French family among whom febrile convulsions (FC) are associated with subsequent temporal lobe epilepsy (TLE) in the same individual, without magnetic resonance imaging-identifiable hippocampal abnormalities [2].
  • A 10-year-old boy developed febrile convulsions at age 2 years, and multiple types of nonfebrile generalized seizures over the ensuing months and years [3].
  • The association between complex febrile convulsions and partial seizures, on the other hand, may reflect either a causal association or the presence of preexisting brain disease that is responsible for both the complex febrile seizures and later partial seizures [4].
  • 10 of these 24 children had temperatures in excess of 38 degrees C and 5 were greater than 40 degrees C. There was a transition in age at presentation between the two groups, with most cot deaths occurring before six months of age and febrile convulsions after that age [5].

Psychiatry related information on FEB1


High impact information on FEB1


Chemical compound and disease context of FEB1


Biological context of FEB1


Anatomical context of FEB1


Associations of FEB1 with chemical compounds


Physical interactions of FEB1


Regulatory relationships of FEB1


Other interactions of FEB1


Analytical, diagnostic and therapeutic context of FEB1


  1. Evidence favoring genetic heterogeneity for febrile convulsions. Racacho, L.J., McLachlan, R.S., Ebers, G.C., Maher, J., Bulman, D.E. Epilepsia (2000) [Pubmed]
  2. Evidence for digenic inheritance in a family with both febrile convulsions and temporal lobe epilepsy implicating chromosomes 18qter and 1q25-q31. Baulac, S., Picard, F., Herman, A., Feingold, J., Genin, E., Hirsch, E., Prud'homme, J.F., Baulac, M., Brice, A., LeGuern, E. Ann. Neurol. (2001) [Pubmed]
  3. A case of extended spectrum GEFS+. Grant, A.C., Vazquez, B. Epilepsia (2005) [Pubmed]
  4. Factors prognostic of unprovoked seizures after febrile convulsions. Annegers, J.F., Hauser, W.A., Shirts, S.B., Kurland, L.T. N. Engl. J. Med. (1987) [Pubmed]
  5. Febrile convulsions and cot death. Sunderland, R., Emery, J.L. Lancet (1981) [Pubmed]
  6. Long-term intellectual and behavioral outcomes of children with febrile convulsions. Verity, C.M., Greenwood, R., Golding, J. N. Engl. J. Med. (1998) [Pubmed]
  7. Postictal and chronic psychoses in patients with temporal lobe epilepsy. Umbricht, D., Degreef, G., Barr, W.B., Lieberman, J.A., Pollack, S., Schaul, N. The American journal of psychiatry. (1995) [Pubmed]
  8. Long-term effect of phenobarbital on cognitive function in children with febrile convulsions. Wolf, S.M., Forsythe, A., Stunden, A.A., Friedman, R., Diamond, H. Pediatrics (1981) [Pubmed]
  9. Prevalence of epilepsy in children of Melipilla, Chile. Chiofalo, N., Kirschbaum, A., Fuentes, A., Cordero, M.L., Madsen, J. Epilepsia (1979) [Pubmed]
  10. Is the long-term outcome of children following febrile convulsions favorable? Kölfen, W., Pehle, K., König, S. Developmental medicine and child neurology. (1998) [Pubmed]
  11. Febrile seizures and generalized epilepsy associated with a mutation in the Na+-channel beta1 subunit gene SCN1B. Wallace, R.H., Wang, D.W., Singh, R., Scheffer, I.E., George, A.L., Phillips, H.A., Saar, K., Reis, A., Johnson, E.W., Sutherland, G.R., Berkovic, S.F., Mulley, J.C. Nat. Genet. (1998) [Pubmed]
  12. Central nervous system effects of the neurohypophyseal hormones and related peptides. de Wied, D., Diamant, M., Fodor, M. Frontiers in neuroendocrinology. (1993) [Pubmed]
  13. Risk of aseptic meningitis after measles, mumps, and rubella vaccine in UK children. Miller, E., Goldacre, M., Pugh, S., Colville, A., Farrington, P., Flower, A., Nash, J., MacFarlane, L., Tettmar, R. Lancet (1993) [Pubmed]
  14. Phenobarbitone in the prophylaxis of febrile convulsions. Stephenson, J.B. Lancet (1981) [Pubmed]
  15. Effectiveness and toxicity of phenobarbital, primidone, and sodium valproate in the prevention of febrile convulsions, controlled by plasma levels. Herranz, J.L., Armijo, J.A., Arteaga, R. Epilepsia (1984) [Pubmed]
  16. Prevention of febrile convulsions with dipropylacetate (Depakine). Cavazzuti, G.B. Epilepsia (1975) [Pubmed]
  17. Febrile convulsions induced by the combination of lipopolysaccharide and low-dose kainic acid enhance seizure susceptibility, not epileptogenesis, in rats. Heida, J.G., Teskey, G.C., Pittman, Q.J. Epilepsia (2005) [Pubmed]
  18. Low CSF GABA concentration in children with febrile convulsions, untreated epilepsy, and meningitis. Rating, D., Siemes, H., Löscher, W. J. Neurol. (1983) [Pubmed]
  19. Molecular genetics of febrile seizures. Iwasaki, N., Nakayama, J., Hamano, K., Matsui, A., Arinami, T. Epilepsia (2002) [Pubmed]
  20. Autosomal dominant epilepsy with febrile seizures plus with missense mutations of the (Na+)-channel alpha 1 subunit gene, SCN1A. Ito, M., Nagafuji, H., Okazawa, H., Yamakawa, K., Sugawara, T., Mazaki-Miyazaki, E., Hirose, S., Fukuma, G., Mitsudome, A., Wada, K., Kaneko, S. Epilepsy Res. (2002) [Pubmed]
  21. Suppression of ventricular ectopy with intravenous metoprolol in patients with chronic obstructive pulmonary disease. Fenster, P.E., Quan, S.F., Hanson, C.D., Coaker, L.A. Crit. Care Med. (1984) [Pubmed]
  22. Homovanillic acid and 5-hydroxyindoleacetic acid in lumbar cerebrospinal fluid in children with afebrile and febrile convulsions. Habel, A., Yates, C.M., McQueen, J.K., Blackwood, D., Elton, R.A. Neurology (1981) [Pubmed]
  23. Volumetric measurements of subcortical nuclei in patients with temporal lobe epilepsy. Dreifuss, S., Vingerhoets, F.J., Lazeyras, F., Andino, S.G., Spinelli, L., Delavelle, J., Seeck, M. Neurology (2001) [Pubmed]
  24. Association of human herpesvirus 6 infection of the central nervous system with recurrence of febrile convulsions. Kondo, K., Nagafuji, H., Hata, A., Tomomori, C., Yamanishi, K. J. Infect. Dis. (1993) [Pubmed]
  25. Placebo-controlled study of phenobarbitone and phenytoin in the prophylaxis of febrile convulsions. Bacon, C.J., Hierons, A.M., Mucklow, J.C., Webb, J.K., Rawlins, M.D., Weightman, D. Lancet (1981) [Pubmed]
  26. gamma-Aminobutyric acid in CSF of children with febrile seizures. Knight, M., Ebert, J., Parish, R.A., Berry, H., Fogelson, M.H. Arch. Neurol. (1985) [Pubmed]
  27. Effects of febrile and epileptic convulsions on daily variations in plasma melatonin concentration in children. Molina-Carballo, A., Acuña-Castroviejo, D., Rodriguez-Cabezas, T., Muñoz-Hoyos, A. J. Pineal Res. (1994) [Pubmed]
  28. Effective short-term diazepam prophylaxis in febrile convulsions. Knudsen, F.U. J. Pediatr. (1985) [Pubmed]
  29. A longitudinal study of valproate free fraction in the specific age group at greatest risk for febrile convulsions (children below 3 years). Monaco, F., Mele, G., Meloni, T., Franca, V., Sotgia, A., Mutani, R. Epilepsia (1984) [Pubmed]
  30. Clinical features and surgical outcome of medial temporal lobe epilepsy with a history of complex febrile convulsions. Janszky, J., Schulz, R., Ebner, A. Epilepsy Res. (2003) [Pubmed]
  31. Posterior fossa malformations and epilepsy. Parmeggiani, A., Posar, A., Scaduto, M.C., Chiodo, S., Santucci, M., Rossi, P.G. J. Child Neurol. (1999) [Pubmed]
  32. The lack of association between febrile convulsions and polymorphisms in SCN1A. Chou, I.C., Peng, C.T., Tsai, F.J., Huang, C.C., Shi, Y.R., Tsai, C.H. Epilepsy Res. (2003) [Pubmed]
  33. Laparoscopic cholecystectomy under epidural anesthesia in patients with chronic respiratory disease. Pursnani, K.G., Bazza, Y., Calleja, M., Mughal, M.M. Surgical endoscopy. (1998) [Pubmed]
  34. The voltage-gated potassium channel KCNQ2 in Taiwanese children with febrile convulsions. Chou, I.C., Tsai, F.J., Huang, C.C., Lin, C.C., Tsai, C.H. Neuroreport (2002) [Pubmed]
  35. Polymorphisms for interleukin 1 beta exon 5 and interleukin 1 receptor antagonist in Taiwanese children with febrile convulsions. Tsai, F.J., Hsieh, Y.Y., Chang, C.C., Lin, C.C., Tsai, C.H. Archives of pediatrics & adolescent medicine. (2002) [Pubmed]
  36. A new method for active surveillance of adverse events from diphtheria/tetanus/pertussis and measles/mumps/rubella vaccines. Farrington, P., Pugh, S., Colville, A., Flower, A., Nash, J., Morgan-Capner, P., Rush, M., Miller, E. Lancet (1995) [Pubmed]
  37. Lumbar puncture and febrile convulsions. Lorber, J., Sunderland, R. Lancet (1980) [Pubmed]
  38. The prognosis for control of seizures with medications in patients with MRI evidence for mesial temporal sclerosis. Kim, W.J., Park, S.C., Lee, S.J., Lee, J.H., Kim, J.Y., Lee, B.I., Kim, D.I. Epilepsia (1999) [Pubmed]
  39. Chaos, balance, and development: thoughts on selected childhood epilepsy syndromes. Vining, E.P. Epilepsia (1990) [Pubmed]
  40. Genetic analysis of febrile convulsions: twin and family studies. Tsuboi, T. Hum. Genet. (1987) [Pubmed]
WikiGenes - Universities