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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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IgA containing circulating immune complexes and IgA anti-single stranded DNA antibodies in patients with obstructive jaundice.

Elevated levels of IgA containing circulating immune complexes (IgA-CIC) and IgG containing (IgG-) CIC were detected in patients with obstructive jaundice due to biliary tract stones and/or tumour of biliary tract or pancreas. Levels of serum IgA were also elevated, and correlated with the levels of IgA-CIC. The levels of IgA and IgG anti-single stranded (ss) DNA were elevated, and there was a significant correlation between the levels of IgA-CIC and IgA anti-ssDNA antibodies. The cause of IgA-CIC increase in patients with obstructive jaundice might be due not only to simple obstruction of biliary tract but also to other factors such as a tissue destruction.[1]

References

  1. IgA containing circulating immune complexes and IgA anti-single stranded DNA antibodies in patients with obstructive jaundice. Ohshio, G., Furukawa, F., Sekita, K., Manabe, T., Tobe, T., Hamashima, Y. Clin. Exp. Immunol. (1985) [Pubmed]
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