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MeSH Review

Biliary Tract

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Disease relevance of Biliary Tract


Psychiatry related information on Biliary Tract


High impact information on Biliary Tract


Chemical compound and disease context of Biliary Tract


Biological context of Biliary Tract


Anatomical context of Biliary Tract


Associations of Biliary Tract with chemical compounds

  • In the obstructed animals, the biliary tree volume measured during taurocholate choleresis (67.4 +/- 15.8 microliters/g liver) was significantly greater than that determined during the increase in bile flow induced by secretin (39.5 +/- 10.4 microliters/g liver) [23].
  • Good cholesterol, bad cholesterol: role of oxysterols in biliary tract diseases [24].
  • The majority of patients with both bilirubin and cholesterol intrahepatic stones had stones throughout the biliary tree simultaneously [25].
  • Biliary secretion of unbiotransformed ceftriaxone occurs at high concentrations; secondary Ca2+ entry results in the formation of supersaturated canalicular bile and subsequent precipitation as a calcium salt in the biliary tract [26].
  • 99mTc bound to [(2,6 dimethylphenylcarbamoylmethyl) iminodiacetic acid] (5 mCi) was administered intravenously to visualize the liver and biliary tract [27].

Gene context of Biliary Tract


Analytical, diagnostic and therapeutic context of Biliary Tract


  1. Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. Sumazaki, R., Shiojiri, N., Isoyama, S., Masu, M., Keino-Masu, K., Osawa, M., Nakauchi, H., Kageyama, R., Matsui, A. Nat. Genet. (2004) [Pubmed]
  2. Utilization of sialic acid as a coreceptor is required for reovirus-induced biliary disease. Barton, E.S., Youree, B.E., Ebert, D.H., Forrest, J.C., Connolly, J.L., Valyi-Nagy, T., Washington, K., Wetzel, J.D., Dermody, T.S. J. Clin. Invest. (2003) [Pubmed]
  3. Mucinous biliary obstruction associated with a cystic adenocarcinoma of the pancreas. Ito, Y., Blackstone, M.O., Frank, P.H., Skinner, D.B. Gastroenterology (1977) [Pubmed]
  4. Nitric oxide-mediated inhibition of DNA repair potentiates oxidative DNA damage in cholangiocytes. Jaiswal, M., LaRusso, N.F., Shapiro, R.A., Billiar, T.R., Gores, G.J. Gastroenterology (2001) [Pubmed]
  5. Autocrine/paracrine regulation of the growth of the biliary tree by the neuroendocrine hormone serotonin. Marzioni, M., Glaser, S., Francis, H., Marucci, L., Benedetti, A., Alvaro, D., Taffetani, S., Ueno, Y., Roskams, T., Phinizy, J.L., Venter, J., Fava, G., Lesage, G.D., Alpini, G. Gastroenterology (2005) [Pubmed]
  6. Controlled study of the effects of tiropramide on biliary dyskinesia. Trabucchi, E., Baratti, C., Centemero, A., Zuin, M., Rizzitelli, E., Colombo, R. Pharmatherapeutica. (1986) [Pubmed]
  7. Epithelial transport in polycystic kidney disease. Sullivan, L.P., Wallace, D.P., Grantham, J.J. Physiol. Rev. (1998) [Pubmed]
  8. Gray-scale ultrasonography and thin-needle cholangiography. Evaluation in the jaundiced patient. Goldstein, L.I., Sample, W.F., Kadell, B.M., Weiner, M. JAMA (1977) [Pubmed]
  9. Elevated carcinoembryonic antigen levels and biliary tract obstruction. Lurie, B.B., Loewenstein, M.S., Zamcheck, N. JAMA (1975) [Pubmed]
  10. Effect of estrogen plus progestin on risk for biliary tract surgery in postmenopausal women with coronary artery disease. The Heart and Estrogen/progestin Replacement Study. Simon, J.A., Hunninghake, D.B., Agarwal, S.K., Lin, F., Cauley, J.A., Ireland, C.C., Pickar, J.H. Ann. Intern. Med. (2001) [Pubmed]
  11. Piperacillin to prevent cholangitis after endoscopic retrograde cholangiopancreatography. A randomized, controlled trial. van den Hazel, S.J., Speelman, P., Dankert, J., Huibregtse, K., Tytgat, G.N., van Leeuwen, D.J. Ann. Intern. Med. (1996) [Pubmed]
  12. Antiepileptic treatment and risk for hepatobiliary cancer and malignant lymphoma. Olsen, J.H., Schulgen, G., Boice, J.D., Whysner, J., Travis, L.B., Williams, G.M., Johnson, F.B., McGee, J.O. Cancer Res. (1995) [Pubmed]
  13. Clinical experience with cefoperazone in biliary tract infections. Mashimo, K. Drugs (1981) [Pubmed]
  14. Outpatient therapy with gemcitabine and docetaxel for gallbladder, biliary, and cholangio-carcinomas. Kuhn, R., Hribaschek, A., Eichelmann, K., Rudolph, S., Fahlke, J., Ridwelski, K. Investigational new drugs. (2002) [Pubmed]
  15. Point mutation of K-ras gene codon 12 in biliary tract tumors. Watanabe, M., Asaka, M., Tanaka, J., Kurosawa, M., Kasai, M., Miyazaki, T. Gastroenterology (1994) [Pubmed]
  16. Primary biliary cirrhosis is a dry gland syndrome with features of chronic graft-versus-host disease. Epstein, O., Thomas, H.C., Sherlock, S. Lancet (1980) [Pubmed]
  17. The onecut transcription factor HNF6 is required for normal development of the biliary tract. Clotman, F., Lannoy, V.J., Reber, M., Cereghini, S., Cassiman, D., Jacquemin, P., Roskams, T., Rousseau, G.G., Lemaigre, F.P. Development (2002) [Pubmed]
  18. Frequency of mutation and deletion of the tumor suppressor gene CDKN2A (MTS1/p16) in hepatocellular carcinoma from an Australian population. Biden, K., Young, J., Buttenshaw, R., Searle, J., Cooksley, G., Xu, D.B., Leggett, B. Hepatology (1997) [Pubmed]
  19. Cancer risk in nontransplanted and transplanted cystic fibrosis patients: a 10-year study. Maisonneuve, P., FitzSimmons, S.C., Neglia, J.P., Campbell, P.W., Lowenfels, A.B. J. Natl. Cancer Inst. (2003) [Pubmed]
  20. Defects in cholangiocyte fibrocystin expression and ciliary structure in the PCK rat. Masyuk, T.V., Huang, B.Q., Ward, C.J., Masyuk, A.I., Yuan, D., Splinter, P.L., Punyashthiti, R., Ritman, E.L., Torres, V.E., Harris, P.C., LaRusso, N.F. Gastroenterology (2003) [Pubmed]
  21. Stimulation of thymidine incorporation in mouse liver and biliary tract epithelium by lithocholate and deoxycholate. Bagheri, S.A., Bolt, M.G., Boyer, J.L., Palmer, R.H. Gastroenterology (1978) [Pubmed]
  22. Mutations of the DPC4/Smad4 gene in biliary tract carcinoma. Hahn, S.A., Bartsch, D., Schroers, A., Galehdari, H., Becker, M., Ramaswamy, A., Schwarte-Waldhoff, I., Maschek, H., Schmiegel, W. Cancer Res. (1998) [Pubmed]
  23. Biliary physiology in rats with bile ductular cell hyperplasia. Evidence for a secretory function of proliferated bile ductules. Alpini, G., Lenzi, R., Sarkozi, L., Tavoloni, N. J. Clin. Invest. (1988) [Pubmed]
  24. Good cholesterol, bad cholesterol: role of oxysterols in biliary tract diseases. Wang, D.Q., Afdhal, N.H. Gastroenterology (2001) [Pubmed]
  25. Gallstones in Western Japan. Factors affecting the prevalence of intrahepatic gallstones. Nagase, M., Hikasa, Y., Soloway, R.D., Tanimura, H., Setoyama, M., Kato, H. Gastroenterology (1980) [Pubmed]
  26. Concentrative biliary secretion of ceftriaxone. Inhibition of lipid secretion and precipitation of calcium ceftriaxone in bile. Xia, Y., Lambert, K.J., Schteingart, C.D., GU, J.J., Hofmann, A.F. Gastroenterology (1990) [Pubmed]
  27. Enterogastric reflux in normal subjects and patients with Bilroth II gastroenterostomy. Measurement of enterogastric reflux. Tolin, R.D., Malmud, L.S., Stelzer, F., Menin, R., Makler, P.T., Applegate, G., Fisher, R.S. Gastroenterology (1979) [Pubmed]
  28. Mutations of p16Ink4/CDKN2 and p15Ink4B/MTS2 genes in biliary tract cancers. Yoshida, S., Todoroki, T., Ichikawa, Y., Hanai, S., Suzuki, H., Hori, M., Fukao, K., Miwa, M., Uchida, K. Cancer Res. (1995) [Pubmed]
  29. Oxysterols induce cyclooxygenase-2 expression in cholangiocytes: implications for biliary tract carcinogenesis. Yoon, J.H., Canbay, A.E., Werneburg, N.W., Lee, S.P., Gores, G.J. Hepatology (2004) [Pubmed]
  30. Bile acids inhibit Mcl-1 protein turnover via an epidermal growth factor receptor/Raf-1-dependent mechanism. Yoon, J.H., Werneburg, N.W., Higuchi, H., Canbay, A.E., Kaufmann, S.H., Akgul, C., Edwards, S.W., Gores, G.J. Cancer Res. (2002) [Pubmed]
  31. Beta-catenin mutations in biliary tract cancers: a population-based study in China. Rashid, A., Gao, Y.T., Bhakta, S., Shen, M.C., Wang, B.S., Deng, J., Fraumeni, J.F., Hsing, A.W. Cancer Res. (2001) [Pubmed]
  32. Membrane-bound carbonic anhydrase IV is expressed in the luminal plasma membrane of the human gallbladder epithelium. Parkkila, S., Parkkila, A.K., Juvonen, T., Waheed, A., Sly, W.S., Saarnio, J., Kaunisto, K., Kellokumpu, S., Rajaniemi, H. Hepatology (1996) [Pubmed]
  33. Biliary excretion of iodipamide. Loeb, P.M., Berk, R.N., Feld, G.K., Wheeler, H.O. Gastroenterology (1975) [Pubmed]
  34. VPAC1 expression is regulated by FXR agonists in the human gallbladder epithelium. Chignard, N., Mergey, M., Barbu, V., Finzi, L., Tiret, E., Paul, A., Housset, C. Hepatology (2005) [Pubmed]
  35. Immunohistochemical analysis of cytokeratin 7 expression in resting and proliferating biliary structures of rat liver. Paku, S., Dezso, K., Kopper, L., Nagy, P. Hepatology (2005) [Pubmed]
  36. Antibiotic prophylaxis in biliary tract surgery. Ciprofloxacin versus ceftriaxone. Kujath, P. Am. J. Med. (1989) [Pubmed]
  37. Pharmacokinetics and biliary concentrations of fleroxacin in cholecystectomized patients. Hayton, W.L., Vlahov, V., Bacracheva, N., Viachki, I., Portmann, R., Muirhead, G., Stoeckel, K., Weidekamm, E. Antimicrob. Agents Chemother. (1990) [Pubmed]
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