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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Major histocompatibility complex-restricted antigen receptor on T cells. VIII. Role of the LFA-1 molecule.

We show that the LFA-1 molecule on T cells does not play a role in the stimulation of T cell hybridomas by certain targets, namely antigen presented by L cell derivatives or polyvalent anti-receptor antibody. These results suggest that LFA-1 may act by binding to ligands that are not present on all cells. We hope this result will help us and others to establish the true role of LFA-1 in T cell responses.[1]

References

  1. Major histocompatibility complex-restricted antigen receptor on T cells. VIII. Role of the LFA-1 molecule. Golde, W.T., Kappler, J.W., Greenstein, J., Malissen, B., Hood, L., Marrack, P. J. Exp. Med. (1985) [Pubmed]
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