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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Rearrangement of nitrogen fixation genes during heterocyst differentiation in the cyanobacterium Anabaena.

Nitrogen fixation by the cyanobacterium Anabaena is carried out in heterocysts, specialized, non-dividing cells which differentiate under conditions of ammonia or nitrate deprivation. In Anabaena, heterocyst differentiation is accompanied by rearrangement of some nitrogen fixation genes. A site-specific recombination between an 11 base-pair direct repeat sequence flanking the nifK and nifD genes removes 11 kilobases of intervening DNA, resulting in juxtaposition of the two genes and an alteration of the nifD protein-coding sequence.[1]


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