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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Combined heart-lung transplantation for terminal pulmonary lymphangioleiomyomatosis.

Combined heart-lung transplantation with cyclosporine is reported in a 26-year-old patient who presented with end-stage pulmonary lymphangioleiomyomatosis. The operation was successful and the patient's rehabilitation excellent over the first 7 postoperative months. She then developed obliterative bronchiolitis of unknown origin. To our knowledge, this is the first published report of an out-hospital survival after heart-lung transplantation for terminal nonvascular lung disease.[1]


  1. Combined heart-lung transplantation for terminal pulmonary lymphangioleiomyomatosis. Wellens, F., Estenne, M., de Francquen, P., Goldstein, J., Leclerc, J.L., Primo, G. J. Thorac. Cardiovasc. Surg. (1985) [Pubmed]
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