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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Effects of glycine and GABA on the ganglion cels of the retina of the skate Raja erinacea.

Application of glycine and GABA caused inhibition of light-evoked activity from different populations of 'ON' center ganglion cells in the retina of the skate (Raja erinacea). Cells affected by glycine were not affected by GABA and vice-versa. Addition of 100 microM strychnine to the glycine-containing perfusate caused a resumption in light-evoked responses of the cells. The action of GABA was antagonized by 100 microM bicuculline methochloride, but not by picrotoxin. Autoradiography revealed the presence of [3H]glycine accumulating amacrine cells.[1]

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