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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Determination of hyoscyamine in BPC mixtures.

The hyoscyamine contents of four BPC mixtures (containing either belladonna or hyoscyamus tincture) were determined using the acid-dye technique. A sample size of 10 ml was required. The mean percentage recovery of hyoscyamine ranged from 99.73 to 101.03 from three mixtures; from the magnesium trisilicate and belladonna mixture, it was 94. 8. The effects of pH and adsorption on the extraction of the alkaloid-dye complex from the mixtures examined are discussed.[1]


  1. Determination of hyoscyamine in BPC mixtures. Khalil, S.A., El-Masry, S. Journal of pharmaceutical sciences. (1976) [Pubmed]
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