Disease relevance of Magnesium trisilicate

• Silica urolithiasis without magnesium trisilicate intake [1].
• Magnesium trisilicate induced fixed drug eruptions [2].
• Comparative study of Algicon suspension and magnesium trisilicate mixture in the treatment of reflux dyspepsia of pregnancy [3].

High impact information on Magnesium trisilicate

• The purpose of this study was to compare the oral bioavailability of silicon and aluminum from Zeolite A, sodium aluminosilicate, magnesium trisilicate, and aluminum hydroxide in dogs [4].
• The prescription of sodium citrate and the H2 receptor antagonist ranitidine has superseded that of Mist. magnesium trisilicate [5].
• Comparison of the prophylactic use of magnesium trisilicate mixture B.P.C., sodium citrate mixture or cimetidine in obstetrics [6].
• Glycopyrrolate, atropine or saline were administered i.v. with oral magnesium trisilicate 1 h before induction of anaesthesia to patients about to undergo Caesarean section [7].
• Due to the adsorption of chloroquine by magnesium trisilicate, both the BP acid absorption test and the rate of hydrochloric acid uptake, as monitored by pH measurements, were significantly reduced [8].

Biological context of Magnesium trisilicate

• Furthermore, MTS provided alkaline microenvironment, which prevented acid-catalyzed hydrolysis and protein unfolding [9].
• Magnesium trisilicate promoted gastric emptying in conventional rats and its antacid effect was observed only in the caecum and colon [10].
• Slight decreased intestinal absorption was shown by magnesium trisilicate (19%) and bismuth carbonate (7%), the other 2 components showing no effects [11].

Anatomical context of Magnesium trisilicate

• 5. The volume of the stomach contents was large and 15 ml of magnesium trisilicate was insufficient to prevent the effects of acid aspiration [12].
• When the magnesium trisilicate mixture was given within the 30 minutes prior to induction of anaesthesia, the number of patients with highly acid gastric content fell to one per cent [13].

Associations of Magnesium trisilicate with other chemical compounds

• The findings suggest that as a means of prophylaxis for Mendelson's syndrome in patients undergoing elective Caesarean section, magnesium trisilicate mixture BPC 20 ml is more effective than a single oral dose of cimetidine 400 mg, administered in the manner described [14].
• The present work describes the effect of magnesium carbonate, magnesium hydroxide, magnesium trisilicate, megaldrate powder, sodium bicarbonate, aluminum oxide and simethicone suspension on the in vitro availability of cefuroxime sodium [15].
• Effect of magnesium trisilicate and kaolin-pectin on the bioavailability of trimethoprim [16].
• Oral metoclopramide, glycopyrrolate and magnesium trisilicate on gastric volume and pH in paediatric patients [17].
• Phenylbutazone bioavailability from an enteric-coated formulation (Butacote) has been studied in normal volunteers following ingestion of a single 200 mg dose with water, aluminium hydroxide and magnesium trisilicate [18].

Gene context of Magnesium trisilicate

• The use of Mist. magnesium trisilicate B.P. as preoperative antacid is urged strongly [19].
• Adsorption of antihypertensives by suspensoids. Part I. The adsorption of propranolol hydrochloride by attapulgite, charcoal, kaolin and magnesium trisilicate [20].

Analytical, diagnostic and therapeutic context of Magnesium trisilicate

• Despite its limitations, magnesium trisilicate remains the most popular antacid during labour and before Caesarean section [21].
• The mean volume aspirated (8 ml) was significantly lower than in a control group receiving magnesium trisilicate (mean volume 30 ml) [22].
• Magnesium trisilicate mixture is an antacid used commonly in our Intensive Care Unit in the prevention and treatment of stress ulcers [23].
• The oral administration of 30 c.c. of magnesium trisilicate has been shown to increase the pH of the gastric contents to above 2.50 in 100 per cent of treated patients, whereas only 60 per cent of the control group were found to have a pH above 2.50 [24].
• A trial was conducted in a third hospital and this showed that a 52 per cent incidence of highly acid gastric juice (pH less than 2.5) in patients prepared for elective surgery was reduced by administration of magnesium trisilicate mixture at the time of premedication [13].

References