Metkephamid-induced Flehmen in lambs.
When metkephamid, a systemically active analog of methionine enkephalin, was administered intracisternally to male or female prepubescent lambs as early as the first week of life, we observed a behavioral pattern akin to Flehmen, which is a well-characterized grimace displayed by mature ungulates during mating. This metkephamid-induced Flehmen was preceded by transient bradycardia and apnea followed by somnolence for approximately 1 hour, during which Flehmen was observed intermittently. Pretreatment with the specific opiate antagonist, naloxone, blocked this behavioral response. These observations indicate that endogenous opioid peptides may be involved in Flehmen.[1]References
- Metkephamid-induced Flehmen in lambs. Donchin, Y., De Vane, G.W., Caton, D. Physiol. Behav. (1984) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
