Wearable artificial endocrine pancrease with needle-type glucose sensor.
Miniaturisation of the bedside artificial endocrine pancreas in necessary to provide a means of restoring physiological glycaemic excursions in diabetic patients in the long term. One of the remaining problems in producing such a sophisticated device is the difficulty in developing a sufficiently small glucose-monitoring system. A needle-type glucose sensor has been developed which is suitable for use in a closed-loop glycaemic control system. The wearable artificial endocrine pancreas, incorporating the needle-type glucose sensor, a computer calculating infusion rates of insulin, glucagon, or both, and infusion pumps, was tested in pancreatectomised dogs: the device produced perfect control of blood glucose for up to 7 days.[1]References
- Wearable artificial endocrine pancrease with needle-type glucose sensor. Shichiri, M., Kawamori, R., Yamasaki, Y., Hakui, N., Abe, H. Lancet (1982) [Pubmed]
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