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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Automated two-site immunoradiometric assay of human alpha-fetoprotein in maternal serum.

Immunoassays of alpha 1-fetoprotein in maternal serum are now in widespread use as a means of antenatal detection of neural tube defects. For population screening to be effective the initial test must be capable of promptly producing reliable results. We describe an automated two-site immunoradiometric assay based on 125I-labeled antibodies and cellulose-coupled antibody, with which up to 100 patients' samples can be assayed in 3 h. The assay is precise, and results obtained agree closely with those produced by conventional radioimmunoassay procedures.[1]

References

  1. Automated two-site immunoradiometric assay of human alpha-fetoprotein in maternal serum. Kemp, H.A., Simpson, J.S., Woodhead, J.S. Clin. Chem. (1981) [Pubmed]
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