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Disease relevance of Radioimmunoassay


Psychiatry related information on Radioimmunoassay


High impact information on Radioimmunoassay

  • Using a sensitive radioimmunoassay, we determined serum immunoreactive erythropoietin levels in 81 anemic patients with solid tumors [11].
  • Radioimmunoassay showed that the concentrations of insulin-like growth factor I (IGF-I) in tumor and serum were low, suggesting feedback inhibition of growth hormone secretion by IGF-II [12].
  • Trough concentrations of serum cyclosporine were measured by radioimmunoassay [13].
  • In 18 of 20 patients with psychosis secondary to systemic lupus erythematosus (SLE), autoantibodies to ribosomal P proteins were detected by immunoblotting and measured with a new radioimmunoassay using a synthetic peptide as antigen [14].
  • Radioimmunoassay confirmed a lower mean estradiol concentration (amenorrheic group, 38.58 pg per milliliter; eumenorrheic group, 106.99 pg per milliliter) and progesterone peak (amenorrheic group, 1.25 ng per milliliter; eumenorrheic group, 12.75 ng per milliliter) in the amenorrheic women, in four venous samples drawn at seven-day intervals [15].

Chemical compound and disease context of Radioimmunoassay


Biological context of Radioimmunoassay


Anatomical context of Radioimmunoassay


Associations of Radioimmunoassay with chemical compounds


Gene context of Radioimmunoassay

  • The JaR cells, and one subline of BeWo, did not express surface HLA-A, -B, and -C (HLA-ABC) antigens, nor did JaR contain the antigens when cell-free extracts were measured in a sensitive radioimmunoassay [35].
  • Results by radioimmunoassay (RIA) for IFN gamma were similar [36].
  • Unstimulated FSC secrete MCP-1 as measured by radioimmunoassay as well as a chemotactic assay and express mRNA that encodes for this cytokine [37].
  • RESULTS: Immunoassay experiments show that MAbs defining the three melanoma antigens bind to affinity-purified ME491 antigen and inhibit each other from binding in an inhibition radioimmunoassay [38].
  • Growth hormone (GH) deficiency, diagnosed by radioimmunoassay (RIA) measurements of GH in blood after provocation or in continuous 24 h samples of venous blood, is usually associated with growth failure [39].

Analytical, diagnostic and therapeutic context of Radioimmunoassay


  1. Prostate-specific antigen as a serum marker for adenocarcinoma of the prostate. Stamey, T.A., Yang, N., Hay, A.R., McNeal, J.E., Freiha, F.S., Redwine, E. N. Engl. J. Med. (1987) [Pubmed]
  2. Evaluation of acromegaly by radioimmunoassay of somatomedin-C. Clemmons, D.R., Van Wyk, J.J., Ridgway, E.C., Kliman, B., Kjellberg, R.N., Underwood, L.E. N. Engl. J. Med. (1979) [Pubmed]
  3. Evidence for viral hepatitis other than type A or type B among persons in Costa Rica. Villarejos, V.M., Visoná, K.A., Eduarte, C.A., Provost, P.J., Hilleman, M.R. N. Engl. J. Med. (1975) [Pubmed]
  4. A comparison of plasma vasopressin measurements with a standard indirect test in the differential diagnosis of polyuria. Zerbe, R.L., Robertson, G.L. N. Engl. J. Med. (1981) [Pubmed]
  5. Hypertyraminemia in cirrhotic patients. Faraj, B.A., Bowen, P.A., Isaacs, J.W., Rudman, D. N. Engl. J. Med. (1976) [Pubmed]
  6. Regional brain concentrations of neuropeptides in Huntington's chorea and schizophrenia. Nemeroff, C.B., Youngblood, W.W., Manberg, P.J., Prange, A.J., Kizer, J.S. Science (1983) [Pubmed]
  7. Methionine and leucine enkephalin in rat neurohypophysis: different responses to osmotic stimuli and T2 toxin. Zamir, N., Zamir, D., Eiden, L.E., Palkovits, M., Brownstein, M.J., Eskay, R.L., Weber, E., Faden, A.I., Feuerstein, G. Science (1985) [Pubmed]
  8. Idiotype-antiidiotype regulation. IV. Expression of common regulatory idiotopes on fructosan-binding and non-fructosan-binding monoclonal immunoglobulin. Goldberg, B., Paul, W.E., Bona, C.A. J. Exp. Med. (1983) [Pubmed]
  9. CSF cholecystokinin concentrations in patients with panic disorder and in normal comparison subjects. Lydiard, R.B., Ballenger, J.C., Laraia, M.T., Fossey, M.D., Beinfeld, M.C. The American journal of psychiatry. (1992) [Pubmed]
  10. Nocturnal excretion of 6-sulphatoxymelatonin in children and adolescents with autistic disorder. Tordjman, S., Anderson, G.M., Pichard, N., Charbuy, H., Touitou, Y. Biol. Psychiatry (2005) [Pubmed]
  11. Decreased erythropoietin response in patients with the anemia of cancer. Miller, C.B., Jones, R.J., Piantadosi, S., Abeloff, M.D., Spivak, J.L. N. Engl. J. Med. (1990) [Pubmed]
  12. Synthesis and secretion of insulin-like growth factor II by a leiomyosarcoma with associated hypoglycemia. Daughaday, W.H., Emanuele, M.A., Brooks, M.H., Barbato, A.L., Kapadia, M., Rotwein, P. N. Engl. J. Med. (1988) [Pubmed]
  13. Serum cyclosporine concentration and risk of acute graft-versus-host disease after allogeneic marrow transplantation. Yee, G.C., Self, S.G., McGuire, T.R., Carlin, J., Sanders, J.E., Deeg, H.J. N. Engl. J. Med. (1988) [Pubmed]
  14. Association between lupus psychosis and anti-ribosomal P protein antibodies. Bonfa, E., Golombek, S.J., Kaufman, L.D., Skelly, S., Weissbach, H., Brot, N., Elkon, K.B. N. Engl. J. Med. (1987) [Pubmed]
  15. Bone mineral content of amenorrheic and eumenorrheic athletes. Drinkwater, B.L., Nilson, K., Chesnut, C.H., Bremner, W.J., Shainholtz, S., Southworth, M.B. N. Engl. J. Med. (1984) [Pubmed]
  16. The regulation of plasma 18-hydroxy 11-deoxycorticosterone in man. Williams, G.H., Braley, L.M., Underwood, R.H. J. Clin. Invest. (1976) [Pubmed]
  17. Gastric mucosal prostaglandin E levels in patients with gastric ulcer disease and carcinoma. Wright, J.P., Young, G.O., Klaff, L.J., Weers, L.A., Price, S.K., Marks, I.N. Gastroenterology (1982) [Pubmed]
  18. Validation and application of a radioimmunoassay for serotonin. Kellum, J.M., Jaffe, B.M. Gastroenterology (1976) [Pubmed]
  19. Purified antigen radioimmunoassay in serological diagnosis of schistosomiasis mansoni. Pelley, R.P., Warren, K.S., Jordan, P. Lancet (1977) [Pubmed]
  20. "Endogenous" benzodiazepine activity in body fluids of patients with hepatic encephalopathy. Mullen, K.D., Szauter, K.M., Kaminsky-Russ, K. Lancet (1990) [Pubmed]
  21. Vitamin D3-induced calcium binding protein in bone tissue. Christakos, S., Norman, A.W. Science (1978) [Pubmed]
  22. Low urinary estrogen glucuronides in women at risk for familial breast cancer. Fishman, J., Fukushima, D.K., O'Connor, J., Lynch, H.T. Science (1979) [Pubmed]
  23. Demonstration and immunochemical characterization of carcinoembryonic antigen in human pancreatic juice. McCabe, R.P., Kupchik, H.Z., Saravis, C.A., Broitman, S.A., Gregg, J.A., Zamcheck, N. J. Natl. Cancer Inst. (1976) [Pubmed]
  24. The ontogenesis of human fetal hormones. III. Prolactin. Aubert, M.J., Grumbach, M.M., Kaplan, S.L. J. Clin. Invest. (1975) [Pubmed]
  25. Multipotential phenotypic expression of genes encoding peptide hormones in rat insulinoma cell lines. Philippe, J., Chick, W.L., Habener, J.F. J. Clin. Invest. (1987) [Pubmed]
  26. Total cortisol in amniotic fluid and fetal lung maturation. de Fencl, M., Tulchinsky, D. N. Engl. J. Med. (1975) [Pubmed]
  27. Melatonin: daily cycle in plasma and cerebrospinal fluid of calves. Hedlund, L., Lischko, M.M., Rollag, M.D., Niswender, G.D. Science (1977) [Pubmed]
  28. Maternal stress alters plasma testosterone in fetal males. Ward, I.L., Weisz, J. Science (1980) [Pubmed]
  29. Pineal melatonin rhythm: reduction in aging Syrian hamsters. Reiter, R.J., Richardson, B.A., Johnson, L.Y., Ferguson, B.N., Dinh, D.T. Science (1980) [Pubmed]
  30. Radioimmunoassay for antibodies to cytoplasmic ribosomes in human serum. Koffler, D., Faiferman, I., Gerber, M.A. Science (1977) [Pubmed]
  31. Inhibition of prostacyclin and platelet thromboxane A2 after low-dose aspirin. Preston, F.E., Whipps, S., Jackson, C.A., French, A.J., Wyld, P.J., Stoddard, C.J. N. Engl. J. Med. (1981) [Pubmed]
  32. Spurious results of digoxin radioimmunoassay. Vinge, E., Nilsson, L.G., Molin, L., Ekman, R. N. Engl. J. Med. (1984) [Pubmed]
  33. Effect of control of blood glucose on urinary excretion of albumin and beta2 microglobulin in insulin-dependent diabetes. Viberti, G.C., Pickup, J.C., Jarrett, R.J., Keen, H. N. Engl. J. Med. (1979) [Pubmed]
  34. Double immunoglobulin production in cloned somatic cell hybrids between two human lymphoid cell lines. Rosén, A., Clements, G., Klein, G., Zeuthen, J. Cell (1977) [Pubmed]
  35. Expression of HLA-A, -B, and -C and beta 2-microglobulin antigens in human choriocarcinoma cell lines. Trowsdale, J., Travers, P., Bodmer, W.F., Patillo, R.A. J. Exp. Med. (1980) [Pubmed]
  36. Decreased production of interferon-gamma by human neonatal cells. Intrinsic and regulatory deficiencies. Wilson, C.B., Westall, J., Johnston, L., Lewis, D.B., Dower, S.K., Alpert, A.R. J. Clin. Invest. (1986) [Pubmed]
  37. Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines. Marra, F., Valente, A.J., Pinzani, M., Abboud, H.E. J. Clin. Invest. (1993) [Pubmed]
  38. ME491 melanoma-associated glycoprotein family: antigenic identity of ME491, NKI/C-3, neuroglandular antigen (NGA), and CD63 proteins. Demetrick, D.J., Herlyn, D., Tretiak, M., Creasey, D., Clevers, H., Donoso, L.A., Vennegoor, C.J., Dixon, W.T., Jerry, L.M. J. Natl. Cancer Inst. (1992) [Pubmed]
  39. Growth without growth hormone: the "invisible" GH syndrome. Bistritzer, T., Chalew, S.A., Lovchik, J.C., Kowarski, A.A. Lancet (1988) [Pubmed]
  40. Familial deficiency of apolipoproteins A-I and C-III and precocious coronary-artery disease. Norum, R.A., Lakier, J.B., Goldstein, S., Angel, A., Goldberg, R.B., Block, W.D., Noffze, D.K., Dolphin, P.J., Edelglass, J., Bogorad, D.D., Alaupovic, P. N. Engl. J. Med. (1982) [Pubmed]
  41. Localisation of substance P immunoreactivity in amacrine cells of the retina. Karten, H.J., Brecha, N. Nature (1980) [Pubmed]
  42. Specific localisation of neurotensin to the N cell in human intestine by radioimmunoassay and immunocytochemistry. Polak, J.M., Sullivan, S.N., Bloom, S.R., Buchan, A.M., Facer, P., Brown, M.R., Pearse, A.G. Nature (1977) [Pubmed]
  43. Circulating atrial natriuretic peptides in conscious rats: regulation of release by multiple factors. Eskay, R., Zukowska-Grojec, Z., Haass, M., Dave, J.R., Zamir, N. Science (1986) [Pubmed]
  44. Antifibrillarin autoantibodies present in systemic sclerosis and other connective tissue diseases interact with similar epitopes. Kasturi, K.N., Hatakeyama, A., Spiera, H., Bona, C.A. J. Exp. Med. (1995) [Pubmed]
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