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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Chlorozotocin treatment of advanced gastrointestinal cancer.

From April 1981 to December 1981, 34 consecutive patients with advanced gastrointestinal cancer were treated with chlorozotocin at the dosage of 40 mg/m2 daily for 5 consecutive days (30 mg/m2 in patients pretreated with chemotherapy) every 6 weeks. In the 30 patients evaluable for response, a 3.3% objective response rate was encountered. Toxicity was not significant and consisted mainly in reversible myelosuppression. Median survival was 3 months. At the dosage and schedule used, chlorozotocin does not seem to be an effective agent in the treatment of advanced gastrointestinal cancer.[1]

References

  1. Chlorozotocin treatment of advanced gastrointestinal cancer. Veronesi, A., Magri, M.D., Tirelli, U., Galligioni, E., Figoli, F., Zagonel, V., Tumolo, S., Grigoletto, E. Med. Pediatr. Oncol. (1983) [Pubmed]
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