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In vitro DNA synthesis by an alpha-like DNA polymerase bound to replicating simian virus 40 chromosomes.

Simian virus 40 chromosomes carry out replicative DNA synthesis in vitro which is sensitive to aphidicolin and to N-ethylmaleimide, resistant to 2',3'-dideoxythymidine-5'-triphosphate, and proportional to the amount of chromosome-associated alpha-like polymerase. Thus, an alpha-like DNA polymerase (alpha polymerase or delta polymerase) is responsible for in vitro DNA synthesis.[1]

References

  1. In vitro DNA synthesis by an alpha-like DNA polymerase bound to replicating simian virus 40 chromosomes. Waqar, M.A., Evans, M.J., Burke, J.F., Tsubota, Y., Plummer, M.J., Huberman, J.A. J. Virol. (1983) [Pubmed]
 
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