- Suppression of frequently recurring genital herpes. A placebo-controlled double-blind trial of oral acyclovir. Straus, S.E., Takiff, H.E., Seidlin, M., Bachrach, S., Lininger, L., DiGiovanna, J.J., Western, K.A., Smith, H.A., Lehrman, S.N., Creagh-Kirk, T. N. Engl. J. Med. (1984)