Chemical Compound Review:
Aciclovir 2-amino-9-(2- hydroxyethoxymethyl)-3H- purin...
Synonyms:
Activir, Virolex, Zovirax, acyclovir, Avirax, ...
- Acyclovir for herpes zoster. van den Broek, P.J., Stuyt, P.M., van der Meer, J.W. N. Engl. J. Med. (1994)
- More on acyclovir for chickenpox. Duvic, M., Grossman, D. N. Engl. J. Med. (1994)
- Brief report: recurrent acyclovir-resistant genital herpes in an immunocompetent patient. Kost, R.G., Hill, E.L., Tigges, M., Straus, S.E. N. Engl. J. Med. (1993)
- Acyclovir to prevent cytomegalovirus infection in renal-graft recipients. Grundy, J.E., Griffiths, P.D. N. Engl. J. Med. (1989)
- Vidarabine versus acyclovir therapy in herpes simplex encephalitis. Whitley, R.J., Alford, C.A., Hirsch, M.S., Schooley, R.T., Luby, J.P., Aoki, F.Y., Hanley, D., Nahmias, A.J., Soong, S.J. N. Engl. J. Med. (1986)
- Acyclovir in Creutzfeldt-Jakob disease. Newman, P.K. Lancet (1984)
- Use of acyclovir for prophylaxis of herpes infections in severely immunocompromised patients. Prentice, H.G. J. Antimicrob. Chemother. (1983)
- Hepatic veno-occlusive disease--liver toxicity syndrome after bone marrow transplantation. Shulman, H.M., Hinterberger, W. Bone Marrow Transplant. (1992)
- Acute confusional state developing in a patient taking acyclovir: from the frying pan into the fire. Goor, Y., Goor, O., Cabili, S. Isr. Med. Assoc. J. (2002)
- Psychological and psychosexual implications of herpes simplex virus infections. Mindel, A. Scandinavian journal of infectious diseases. Supplementum. (1996)
- Acyclovir for recurrent herpes simplex virus ocular disease. Jabs, D.A. N. Engl. J. Med. (1998)
- More on continuous-infusion acyclovir for severe varicella. Krolewiecki, A.J., Braffman, M. N. Engl. J. Med. (1997)
- A randomized trial of acyclovir for 7 days or 21 days with and without prednisolone for treatment of acute herpes zoster. Wood, M.J., Johnson, R.W., McKendrick, M.W., Taylor, J., Mandal, B.K., Crooks, J. N. Engl. J. Med. (1994)
- A controlled trial comparing vidarabine with acyclovir in neonatal herpes simplex virus infection. Infectious Diseases Collaborative Antiviral Study Group. Whitley, R., Arvin, A., Prober, C., Burchett, S., Corey, L., Powell, D., Plotkin, S., Starr, S., Alford, C., Connor, J. N. Engl. J. Med. (1991)
- Predictors of morbidity and mortality in neonates with herpes simplex virus infections. The National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Whitley, R., Arvin, A., Prober, C., Corey, L., Burchett, S., Plotkin, S., Starr, S., Jacobs, R., Powell, D., Nahmias, A. N. Engl. J. Med. (1991)
- A controlled trial comparing foscarnet with vidarabine for acyclovir-resistant mucocutaneous herpes simplex in the acquired immunodeficiency syndrome. The AIDS Clinical Trials Group. Safrin, S., Crumpacker, C., Chatis, P., Davis, R., Hafner, R., Rush, J., Kessler, H.A., Landry, B., Mills, J. N. Engl. J. Med. (1991)
- A trial of topical acyclovir in genital herpes simplex virus infections. Corey, L., Nahmias, A.J., Guinan, M.E., Benedetti, J.K., Critchlow, C.W., Holmes, K.K. N. Engl. J. Med. (1982)
- Acyclovir treatment of the chronic fatigue syndrome. Lack of efficacy in a placebo-controlled trial. Straus, S.E., Dale, J.K., Tobi, M., Lawley, T., Preble, O., Blaese, R.M., Hallahan, C., Henle, W. N. Engl. J. Med. (1988)
- Treatment of first episodes of genital herpes simplex virus infection with oral acyclovir. A randomized double-blind controlled trial in normal subjects. Bryson, Y.J., Dillon, M., Lovett, M., Acuna, G., Taylor, S., Cherry, J.D., Johnson, B.L., Wiesmeier, E., Growdon, W., Creagh-Kirk, T., Keeney, R. N. Engl. J. Med. (1983)
- Suppression of frequently recurring genital herpes. A placebo-controlled double-blind trial of oral acyclovir. Straus, S.E., Takiff, H.E., Seidlin, M., Bachrach, S., Lininger, L., DiGiovanna, J.J., Western, K.A., Smith, H.A., Lehrman, S.N., Creagh-Kirk, T. N. Engl. J. Med. (1984)
- Possible drug interaction during therapy with azidothymidine and acyclovir for AIDS. Bach, M.C. N. Engl. J. Med. (1987)
- Altered substrate specificity of herpes simplex virus thymidine kinase confers acyclovir-resistance. Darby, G., Field, H.J., Salisbury, S.A. Nature (1981)
- Prophylactic acyclovir in patients receiving bone marrow transplants. Trigg, M.E., Finlay, J.L., Sondel, P.M. N. Engl. J. Med. (1985)
- Epstein-Barr virus-induced B-cell lymphoma after renal transplantation: acyclovir therapy and transition from polyclonal to monoclonal B-cell proliferation. Hanto, D.W., Frizzera, G., Gajl-Peczalska, K.J., Sakamoto, K., Purtilo, D.T., Balfour, H.H., Simmons, R.L., Najarian, J.S. N. Engl. J. Med. (1982)
- A randomized, placebo-controlled trial of oral acyclovir for the prevention of cytomegalovirus disease in recipients of renal allografts. Balfour, H.H., Chace, B.A., Stapleton, J.T., Simmons, R.L., Fryd, D.S. N. Engl. J. Med. (1989)
- Herpes simplex virus infection of human fibroblasts and keratinocytes inhibits recognition by cloned CD8+ cytotoxic T lymphocytes. Koelle, D.M., Tigges, M.A., Burke, R.L., Symington, F.W., Riddell, S.R., Abbo, H., Corey, L. J. Clin. Invest. (1993)
- Drugs five years later: acyclovir. Dorsky, D.I., Crumpacker, C.S. Ann. Intern. Med. (1987)
- Treatment of varicella-zoster virus infection in severely immunocompromised patients. A randomized comparison of acyclovir and vidarabine. Shepp, D.H., Dandliker, P.S., Meyers, J.D. N. Engl. J. Med. (1986)
- Randomised comparison of ganciclovir and high-dose acyclovir for long-term cytomegalovirus prophylaxis in liver-transplant recipients. Winston, D.J., Wirin, D., Shaked, A., Busuttil, R.W. Lancet (1995)
- Progressive esophagitis from acyclovir-resistant herpes simplex. Clinical roles for DNA polymerase mutants and viral heterogeneity? Sacks, S.L., Wanklin, R.J., Reece, D.E., Hicks, K.A., Tyler, K.L., Coen, D.M. Ann. Intern. Med. (1989)
- Acyclovir with and without prednisone for the treatment of herpes zoster. A randomized, placebo-controlled trial. The National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Whitley, R.J., Weiss, H., Gnann, J.W., Tyring, S., Mertz, G.J., Pappas, P.G., Schleupner, C.J., Hayden, F., Wolf, J., Soong, S.J. Ann. Intern. Med. (1996)
- 2-Acetylpyridine 5-[(dimethylamino)thiocarbonyl]-thiocarbonohydrazone (A1110U), a potent inactivator of ribonucleotide reductases of herpes simplex and varicella-zoster viruses and a potentiator of acyclovir. Spector, T., Harrington, J.A., Morrison, R.W., Lambe, C.U., Nelson, D.J., Averett, D.R., Biron, K., Furman, P.A. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Enzymatic therapeutic index of acyclovir. Viral versus human polymerase gamma specificity. Hanes, J.W., Zhu, Y., Parris, D.S., Johnson, K.A. J. Biol. Chem. (2007)
- Inhibition of tumor growth by direct intratumoral gene transfer of herpes simplex virus thymidine kinase gene with DNA-liposome complexes. Sugaya, S., Fujita, K., Kikuchi, A., Ueda, H., Takakuwa, K., Kodama, S., Tanaka, K. Hum. Gene Ther. (1996)
- Gene expression in the human intestine and correlation with oral valacyclovir pharmacokinetic parameters. Landowski, C.P., Sun, D., Foster, D.R., Menon, S.S., Barnett, J.L., Welage, L.S., Ramachandran, C., Amidon, G.L. J. Pharmacol. Exp. Ther. (2003)
- Inhibitory effects of IFN-gamma and acyclovir on the glioblastoma cell cycle. Kominsky, S.L., Subramaniam, P.S., Johnson, H.M., Torres, B.A. J. Interferon Cytokine Res. (2000)
- Identification and analysis of the simian varicella virus thymidine kinase gene. Pumphrey, C.Y., Gray, W.L. Arch. Virol. (1996)
- Adenovirus-mediated suicide-gene therapy using the herpes simplex virus thymidine kinase gene in cell and animal models of human prostate cancer: changes in tumour cell proliferative activity. Cheon, J., Kim, H.K., Moon, D.G., Yoon, D.K., Cho, J.H., Koh, S.K. BJU international. (2000)
- Acyclovir for prevention of cytomegalovirus infection and disease after allogeneic marrow transplantation. Meyers, J.D., Reed, E.C., Shepp, D.H., Thornquist, M., Dandliker, P.S., Vicary, C.A., Flournoy, N., Kirk, L.E., Kersey, J.H., Thomas, E.D. N. Engl. J. Med. (1988)
- Persistence of immunity to varicella in children with leukemia immunized with live attenuated varicella vaccine. Gershon, A.A., Steinberg, S.P. N. Engl. J. Med. (1989)
- A double-blind study of oral acyclovir for suppression of recurrences of genital herpes simplex virus infection. Douglas, J.M., Critchlow, C., Benedetti, J., Mertz, G.J., Connor, J.D., Hintz, M.A., Fahnlander, A., Remington, M., Winter, C., Corey, L. N. Engl. J. Med. (1984)