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Activation of 2-aminofluorene by cultured plant cells.

Cultured tobacco plant cells activated 2-aminofluorene to an agent mutagenic to Salmonella typhimurium strain TA98. The plant activation of 2-aminofluorene is heat-inactivated and may not involve solely cytochrome P-450. The kinetics of activation demonstrated both time- and concentration-dependent responses.[1]


  1. Activation of 2-aminofluorene by cultured plant cells. Plewa, M.J., Weaver, D.L., Blair, L.C., Gentile, J.M. Science (1983) [Pubmed]
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