The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

About

Terms

 

 
 
 
 

Inhibition by aminoacetonitrile and propargylamine of glycine cleavage system from rat brain and liver mitochondria.

Glycine degradation in the CNS is catalyzed by the glycine cleavage system ( GCS). We have tested several compounds with a structural analogy to glycine for their inhibition of the GCS. Compounds having an inhibitory activity, such as aminoacetonitrile and propargylamine, are characterized by having a primary amine group and a pi-electron system present in the group substituting for the carboxylic function. The inhibition by these compounds of glycine degradation may be of pharmacological interest given the neurotransmitter role of glycine.[1]

References

  1. Inhibition by aminoacetonitrile and propargylamine of glycine cleavage system from rat brain and liver mitochondria. Benavides, J., Croci, N., Strolin Benedetti, M. Biochem. Pharmacol. (1983) [Pubmed]
Annotations and hyperlinks in this abstract are from individual authors of WikiGenes or automatically generated by the WikiGenes Data Mining Engine. The abstract is from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities