The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Impaired osmoregulation at high altitude. Studies on Mt Everest.

Osmoregulation was studied in 13 mountaineers who had experienced long-term exposure to high altitude on Mt Everest. Serum osmolality rose from 290 +/- 1 mOsm/kg to 295 +/- 2 mOsm/kg at 5,400 m and finally to 302 +/- 4 mOsm/kg at 6,300 m after a mean of 26.5 days above 5,400 m. Despite this degree of osmoconcentration, plasma arginine-vasopressin concentration remained unchanged: 1.1 +/-0.1 microU/mL at sea level, 0.8 +/- 0.1 microU/mL at 5,400 m, and 0.9 +/- 0.1 microU/mL at 6,300 m. Urinary vasopressin excretion was also similar at all three altitudes. We conclude that prolonged exposure to high altitude may result in persistent impairment of osmoregulation, caused in part by an inappropriate arginine-vasopressin response to hyperosmolality.[1]

References

  1. Impaired osmoregulation at high altitude. Studies on Mt Everest. Blume, F.D., Boyer, S.J., Braverman, L.E., Cohen, A., Dirkse, J., Mordes, J.P. JAMA (1984) [Pubmed]
 
WikiGenes - Universities