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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Tetrabenazine and movement disorders.

Based on blind review of videotape recordings, we analyzed the ability of tetrabenazine to suppress abnormal movements. The recordings were done before treatment, after 3 weeks on a stable dose (up to 200 mg daily) of tetrabenazine, and then after 3 weeks on placebo. Among the patients who completed the trial, improvement occurred in 6 of 8 with Huntington disease, 6 of 10 with tardive dyskinesia, and 3 of 8 with dystonic disorders. The drug was usually tolerated well.[1]


  1. Tetrabenazine and movement disorders. Asher, S.W., Aminoff, M.J. Neurology (1981) [Pubmed]
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