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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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A multinuclear NMR study of 2,3-bisphosphoglycerate metabolism in the human erythrocyte.

Resonances from 13C, 31P and 1H have been detected simultaneously in suspensions of human erythrocytes using a modified NMR spectrometer equipped with a probe tuned to four different frequencies. The utility of multinuclear NMR in the study of cellular metabolism is demonstrated with an investigation of 13C label flux through the 2,3-bisphosphoglycerate bypass in human erythrocytes. In a single experiment, the respective contributions of this bypass and the pentose-phosphate shunt were found to be 27 and 10% of the total glycolytic rate.[1]

References

  1. A multinuclear NMR study of 2,3-bisphosphoglycerate metabolism in the human erythrocyte. Oxley, S.T., Porteous, R., Brindle, K.M., Boyd, J., Campbell, I.D. Biochim. Biophys. Acta (1984) [Pubmed]
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