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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Phase II evaluation of L-alanosine (NSC-153353) for patients with disseminated malignant melanoma.

The authors conducted a phase II study of L-alanosine in 39 patients (19 without prior chemotherapy) in advanced malignant melanoma. The intravenous dose was 250 mg/m2/days 1-3 repeated at 3-week intervals. There were two objective regressions (5%) in conjunction with generally transient and tolerable hematologic and gastrointestinal toxicity. L-alanosine as used in our study has limited activity against malignant melanoma.[1]

References

  1. Phase II evaluation of L-alanosine (NSC-153353) for patients with disseminated malignant melanoma. Creagan, E.T., Long, H.J., Ahmann, D.L., Green, S.J. Am. J. Clin. Oncol. (1984) [Pubmed]
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