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Cooke, H.J. et al.

Evolution of a human Y chromosome-specific repeated sequence.

The structure and evolution of a repetitive sequence on the human Y chromosome has been studied by restriction enzyme analysis of both total DNA and the isolated sequence. The sequence is shown to cross-hybridize to sequences in female DNA forming unstable duplexes. Mouse/human cell hybrids have been used to investigate the pattern of sequence homology on the X chromosome and some autosomes. We conclude that this sequence is related to human satellite III, but shows considerable differences in structure.[1]

References

Evolution of a human Y chromosome-specific repeated sequence. Cooke, H.J., McKay, R.D. Cell (1978) [Pubmed]

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