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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Localisation of genetic markers and orientation of the linkage group on chromosome 19.

A panel of human-rodent somatic cell hybrids containing translocation derivatives of human chromosome 19 has been used to assign the markers peptidase D, complement component 3, lysosomal mannosidase, lysosomal DNAase, chorionic gonadotropin beta-subunit, and a new polymorphic DNA sequence, to specific regions of chromosome 19. This has allowed the relative orientations of the genetic and physical maps to be established, and provides the framework for a search for the genes responsible for inherited disorders on chromosome 19, such as myotonic dystrophy and neurofibromatosis.[1]

References

  1. Localisation of genetic markers and orientation of the linkage group on chromosome 19. Brook, J.D., Shaw, D.J., Meredith, L., Bruns, G.A., Harper, P.S. Hum. Genet. (1984) [Pubmed]
 
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