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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Epidermal growth factor and tumor promoters prevent DNA fragmentation by different mechanisms.

Serum deprivation of C3H 10T 1/2 fibroblasts resulted in DNA fragmentation which was prevented by growth factors such as Epidermal Growth Factor or the tumor promoters, 12-0-tetradecanoyl-13-0-phorbol acetate and Dihydroteleocidin B. Palmityl carnitine, an inhibitor of Ca2+-phospholipid-dependent protein kinase C, reversed the effects of the tumor promoters, but not the effect of Epidermal Growth Factor.[1]

References

  1. Epidermal growth factor and tumor promoters prevent DNA fragmentation by different mechanisms. Kanter, P., Leister, K.J., Tomei, L.D., Wenner, P.A., Wenner, C.E. Biochem. Biophys. Res. Commun. (1984) [Pubmed]
 
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