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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Properdin factor b-polymorphism in the population of Hessen, Germany.

The polymorphism of properdin factor B (Bf, C3 proactivator) in a population sample from Hessen, Germany has been investigated by agarose gel electrophoresis and immunofixation. In 522 unrelated individuals seven different phenotypes were observed and the following allele frequencies calculated: BfS = 0.7998, BfF = 0.1772, BfS0.7 = 0.0163 and BfF1 = 0.0077. Investigations of 100 families with 198 children and 30 mother-child combinations support the assumed autosomal codominant way of inheritance.[1]


  1. Properdin factor b-polymorphism in the population of Hessen, Germany. Kühnl, P., Spielmann, W. Z. Rechtsmed. (1978) [Pubmed]
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