Gene Review:
CFP - complement factor properdin
Homo sapiens
Synonyms:
BFD, Complement factor P, PFC, PFD, PROPERDIN, ...
- Complement system in pneumococcal infections. Reed, W.P., Davidson, M.S., Williams, R.C. Infect. Immun. (1976)
- Localization of the properdin structural locus to Xp11.23-Xp21.1. Goundis, D., Holt, S.M., Boyd, Y., Reid, K.B. Genomics (1989)
- Properdin deficiency in a family with fulminant meningococcal infections. Sjöholm, A.G., Braconier, J.H., Söderström, C. Clin. Exp. Immunol. (1982)
- Association between combined properdin and mannose-binding lectin deficiency and infection with Neisseria meningitidis. Bathum, L., Hansen, H., Teisner, B., Koch, C., Garred, P., Rasmussen, K., Wang, P. Mol. Immunol. (2006)
- Properdin deficiency with IgA nephropathy. Wyatt, R.J., Julian, B.A., Galla, J.H. N. Engl. J. Med. (1981)
- Arthritis associated with intestinal-bypass procedure for morbid obesity. Complement activation and characterization of circulating cryoproteins. Wands, J.R., LaMont, J.T., Mann, E., Isselbacher, K.J. N. Engl. J. Med. (1976)
- Activation of the properdin pathway of complement in patients with gram-negative of bacteremia. Fearon, D.T., Ruddy, S., Schur, P.H., McCabe, W.R. N. Engl. J. Med. (1975)
- A highly conserved amino-acid sequence in thrombospondin, properdin and in proteins from sporozoites and blood stages of a human malaria parasite. Robson, K.J., Hall, J.R., Jennings, M.W., Harris, T.J., Marsh, K., Newbold, C.I., Tate, V.E., Weatherall, D.J. Nature (1988)
- Babesia rodhaini: requirement of complement for penetration of human erythrocytes. Chapman, W.E., Ward, P.A. Science (1977)
- Analysis of the interactions between properdin, the third component of complement (C3), and its physiological activation products. Farries, T.C., Lachmann, P.J., Harrison, R.A. Biochem. J. (1988)
- Genetic and physical mapping around the properdin P gene. Coleman, M.P., Murray, J.C., Willard, H.F., Nolan, K.F., Reid, K.B., Blake, D.J., Lindsay, S., Bhattacharya, S.S., Wright, A., Davies, K.E. Genomics (1991)
- Activation of the alternative (properdin) pathway by divalent cations. Lew, F.T., Yukiyama, Y., Waks, H.S., Osler, A.G. J. Immunol. (1975)
- Molecular characterization of properdin deficiency type III: dysfunction produced by a single point mutation in exon 9 of the structural gene causing a tyrosine to aspartic acid interchange. Fredrikson, G.N., Westberg, J., Kuijper, E.J., Tijssen, C.C., Sjöholm, A.G., Uhlén, M., Truedsson, L. J. Immunol. (1996)
- Analysis of the interaction between properdin and factor B, components of the alternative-pathway C3 convertase of complement. Farries, T.C., Lachmann, P.J., Harrison, R.A. Biochem. J. (1988)
- Inhibition of APP trafficking by tau protein does not increase the generation of amyloid-beta peptides. Goldsbury, C., Mocanu, M.M., Thies, E., Kaether, C., Haass, C., Keller, P., Biernat, J., Mandelkow, E., Mandelkow, E.M. Traffic (2006)
- Properdin, a positive regulator of complement activation, is released from secondary granules of stimulated peripheral blood neutrophils. Wirthmueller, U., Dewald, B., Thelen, M., Schäfer, M.K., Stover, C., Whaley, K., North, J., Eggleton, P., Reid, K.B., Schwaeble, W.J. J. Immunol. (1997)
- Depressed synovial fluid levels of properdin and properdin factor B in patients with rheumatoid arthritis. Ruddy, S., Fearon, D.T., Austen, K.F. Arthritis Rheum. (1975)
- Cleavage of the third complement component (C3) and generation of the spasmogenic peptide, C3a, in human serum via the properdin pathway: demonstration of inhibitory as well as enhancing effects of epsilon-amino-caproic acid. Vogt, W., Schmidt, G., Lynen, R., Dieminger, L. J. Immunol. (1975)
- Histidine-rich glycoprotein inhibits the antiangiogenic effect of thrombospondin-1. Simantov, R., Febbraio, M., Crombie, R., Asch, A.S., Nachman, R.L., Silverstein, R.L. J. Clin. Invest. (2001)
- Surface-dependent modulation by H of C5 cleavage by the cell-bound alternative pathway C5 convertase of human complement. Fischer, E., Kazatchkine, M.D. J. Immunol. (1983)
- Modulation of TNF-alpha secretion in peripheral blood mononuclear cells by cocoa flavanols and procyanidins. Mao, T.K., van de Water, J., Keen, C.L., Schmitz, H.H., Gershwin, M.E. Dev. Immunol. (2002)
- Serum amyloid A, properdin, complement 3, and toll-like receptors are expressed locally in human sinonasal tissue. Lane, A.P., Truong-Tran, Q.A., Myers, A., Bickel, C., Schleimer, R.P. American journal of rhinology. (2006)
- Glomerular deposition of mannose-binding lectin (MBL) indicates a novel mechanism of complement activation in IgA nephropathy. Endo, M., Ohi, H., Ohsawa, I., Fujita, T., Matsushita, M., Fujita, T. Nephrol. Dial. Transplant. (1998)
- Development and application of an enzyme-linked immunosorbent assay for the quantitation of alternative complement pathway activation in human serum. Mayes, J.T., Schreiber, R.D., Cooper, N.R. J. Clin. Invest. (1984)
- The role of properdin in the assembly of the alternative pathway C3 convertases of complement. Hourcade, D.E. J. Biol. Chem. (2006)
- Molecular cloning of the cDNA coding for properdin, a positive regulator of the alternative pathway of human complement. Nolan, K.F., Schwaeble, W., Kaluz, S., Dierich, M.P., Reid, K.B. Eur. J. Immunol. (1991)