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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Effect of a single dose of dimethyl sulphoxide on renal amyloidosis.

An amyloid-like fibrillar substance was obtained under certain chemical conditions from the urine of 11 patients with amyloid nephropathy who had been given a test dose of dimethyl sulphoxide. This fibrillar material could not be produced in the urine from 9 patients with proteinuria due to other causes. This finding may be useful in the diagnosis of amyloid nephropathy and could lead to a new approach to thearpy.[1]


  1. Effect of a single dose of dimethyl sulphoxide on renal amyloidosis. Ravid, M., Keizman, I.K., Sohar, E. Lancet (1977) [Pubmed]
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