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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Reversal of simian virus 40 small-t-antigen-induced theophylline resistance.

Simian virus 40 small-t antigen allows the growth of CV-1 cells in concentrations of theophylline that normally prevent cell cycling. This effect is completely overcome by two ionophores that uncouple mitochondria and by the anti-mitochondrial drug methylglyoxal bis-(guanylhydrazone).[1]


  1. Reversal of simian virus 40 small-t-antigen-induced theophylline resistance. Rundell, K., Calenoff, M., Renz, C. J. Virol. (1984) [Pubmed]
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