Gene Review:
SV40gp7 - small t antigen
Simian virus 40
- Control of protein phosphatase 2A by simian virus 40 small-t antigen. Yang, S.I., Lickteig, R.L., Estes, R., Rundell, K., Walter, G., Mumby, M.C. Mol. Cell. Biol. (1991)
- The SV40 small t-antigen prevents mammary gland differentiation and induces breast cancer formation in transgenic mice; truncated large T-antigen molecules harboring the intact p53 and pRb binding region do not have this effect. Goetz, F., Tzeng, Y.J., Guhl, E., Merker, J., Graessmann, M., Graessmann, A. Oncogene (2001)
- Simian virus 40 large T-antigen, but not small T-antigen, trans-activates the human cytomegalovirus major immediate early promoter. Moens, U., Van Ghelue, M., Kristoffersen, A.K., Johansen, B., Rekvig, O.P., Degré, M., Rollag, H. Virus Genes (2001)
- SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen. Bikel, I., Montano, X., Agha, M.E., Brown, M., McCormack, M., Boltax, J., Livingston, D.M. Cell (1987)
- Role of the amino-terminal domain of simian virus 40 early region in inducing tumors in secretin-expressing cells in transgenic mice. Ratineau, C., Ronco, A., Leiter, A.B. Gastroenterology (2000)
- Multiple tumor suppressor pathways negatively regulate telomerase. Lin, S.Y., Elledge, S.J. Cell (2003)
- trans-activation of RNA polymerase II and III promoters by SV40 small t antigen. Loeken, M., Bikel, I., Livingston, D.M., Brady, J. Cell (1988)
- Polyoma and SV40 proteins differentially regulate PP2A to activate distinct cellular signaling pathways involved in growth control. Rodriguez-Viciana, P., Collins, C., Fried, M. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Isolation and characterization of NIH 3T3 cells expressing polyomavirus small T antigen. Noda, T., Satake, M., Robins, T., Ito, Y. J. Virol. (1986)
- Nuclear transport of proteins translated in vitro from SP6 plasmid-generated mRNAs. Parnaik, V.K., Kennady, P.K. Mol. Cell. Biol. (1990)
- Reversal of simian virus 40 small-t-antigen-induced theophylline resistance. Rundell, K., Calenoff, M., Renz, C. J. Virol. (1984)
- Effect of zinc ions on the biochemical behavior of simian virus 40 small-t antigen expressed in bacteria. Goswami, R., Turk, B., Enderle, K., Howe, A., Rundell, K. J. Virol. (1992)
- Simian virus 40 small-t antigen-induced theophylline resistance is not mediated by cyclic AMP. Renz, C., Rundell, K. J. Virol. (1985)
- Inhibition of lens fiber cell morphogenesis by expression of a mutant SV40 large T antigen that binds CREB-binding protein/p300 but not pRb. Chen, Q., Liang, D., Fromm, L.D., Overbeek, P.A. J. Biol. Chem. (2004)
- Nucleotide sequence analysis of viable deletion mutants lacking segments of the simian virus 40 genome coding for small t antigen. Thimmappaya, B., Shenk, T. J. Virol. (1979)
- Nucleotide sequence deletions within the coding region for small-t antigen of simian virus 40. Volckaert, G., Feunteun, J., Crawford, L.V., Berg, P., Fiers, W. J. Virol. (1979)
- Cell adhesion markers are expressed by a stable human endothelial cell line transformed by the SV40 large T antigen under vimentin promoter control. Vicart, P., Testut, P., Schwartz, B., Llorens-Cortes, C., Perdomo, J.J., Paulin, D. J. Cell. Physiol. (1993)
- Conditional immortalization of normal and dysgenic mouse muscle cells by the SV40 large T antigen under the vimentin promoter control. Pinçon-Raymond, M., Vicart, P., Bois, P., Chassande, O., Romey, G., Varadi, G., Li, Z.L., Lazdunski, M., Rieger, F., Paulin, D. Dev. Biol. (1991)
- The SV40 small t antigen is essential for the morphological transformation of human fibroblasts. de Ronde, A., Sol, C.J., van Strien, A., ter Schegget, J., van der Noordaa, J. Virology (1989)
- Recombinant retroviruses that transduce individual polyoma tumor antigens: effects on growth and differentiation. Cherington, V., Morgan, B., Spiegelman, B.M., Roberts, T.M. Proc. Natl. Acad. Sci. U.S.A. (1986)
- Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes. Ugi, S., Imamura, T., Maegawa, H., Egawa, K., Yoshizaki, T., Shi, K., Obata, T., Ebina, Y., Kashiwagi, A., Olefsky, J.M. Mol. Cell. Biol. (2004)
- Protein phosphatase 2A forms a molecular complex with Shc and regulates Shc tyrosine phosphorylation and downstream mitogenic signaling. Ugi, S., Imamura, T., Ricketts, W., Olefsky, J.M. Mol. Cell. Biol. (2002)
- Association of simian virus 40 small-t antigen with the 61-kilodalton component of a cellular protein complex. Joshi, B., Rundell, K. J. Virol. (1990)
- Inhibition of PP2A, but not PP5, mediates p53 activation by low levels of okadaic acid in rat liver epithelial cells. Messner, D.J., Romeo, C., Boynton, A., Rossie, S. J. Cell. Biochem. (2006)
- The T/t common region of simian virus 40 large T antigen contains a distinct transformation-governing sequence. Marsilio, E., Cheng, S.H., Schaffhausen, B., Paucha, E., Livingston, D.M. J. Virol. (1991)
- Development, progression, and androgen-dependence of prostate tumors in probasin-large T antigen transgenic mice: a model for prostate cancer. Kasper, S., Sheppard, P.C., Yan, Y., Pettigrew, N., Borowsky, A.D., Prins, G.S., Dodd, J.G., Duckworth, M.L., Matusik, R.J. Lab. Invest. (1998)
- The detection of simian virus 40 in human tumors by polymerase chain reaction. Rizzo, P., Di Resta, I., Powers, A., Matker, C.M., Zhang, A., Mutti, L., Kast, W.M., Pass, H., Carbone, M. Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace / Fondazione clinica del lavoro, IRCCS [and] Istituto di clinica tisiologica e malattie apparato respiratorio, Università di Napoli, Secondo ateneo. (1998)
- A novel in vivo transcription assay demonstrates the presence of globin-inducing trans-acting factors in uninduced murine erythroleukemia cells. Wrighton, N., Grosveld, F. Mol. Cell. Biol. (1988)