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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
 
 
 
 

Microbial biodegradation of 4-chlorobiphenyl, a model compound of chlorinated biphenyls.

The biodegradation products of 4-chlorobiphenyl were analyzed in an Achromobacter sp. strain and a Bacillus brevis strain. Both strains generated the same metabolites, with 4-chlorobenzoic acid as the major metabolic product. Our results corroborate previous observations whereby most bacterial strains degrade the chlorobiphenyls via a major pathway which proceeds by an hydroxylation in position 2,3 and a meta-1,2 fission. However, we also detected several metabolites whose structure suggests the existence of other routes for the degradation of chlorinated biphenyls.[1]

References

  1. Microbial biodegradation of 4-chlorobiphenyl, a model compound of chlorinated biphenyls. Massé, R., Messier, F., Péloquin, L., Ayotte, C., Sylvestre, M. Appl. Environ. Microbiol. (1984) [Pubmed]
 
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