The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Thyroxine toxicosis. A common variant of hyperthyroidism.

To determine the frequency of thyroxine (T4) toxicosis, we calculated a free triiodothyronine index (FT3I) on 124 patients who displayed elevations of the free T4 index (FT4I) on initial screening. If the clinical presentation was not characteristic of hyperthyroidism or if the FT3I was not elevated, a thyrotropin-releasing hormone (TRH) test was performed. Of 83 hyperthryoid patients, 70 displayed elevations of both the FT4 and FT3 indices. Thirteen patients, however, had elevations of the FT4I alone. This frequency of T4 toxicosis is higher than generally appreciated. Forty-one patients, most of whom were ill with nonthyroidal diseases, had normal TRH test results and were classified euthyroid. We conclude that FT4I elevations owing to T4 toxicosis and nonthyroidal illnesses are common and that the laboratory differentiation between the syndromes may be difficult.[1]


  1. Thyroxine toxicosis. A common variant of hyperthyroidism. Caplan, R.H., Pagliara, A.S., Wickus, G. JAMA (1980) [Pubmed]
WikiGenes - Universities