The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Relaxin stimulates plasminogen activator secretion by rat granulosa cells in vitro.

Granulosa cells isolated from the ovaries of pregnant mare serum gonadotropin (PMSG)-treated immature rats were cultured with relaxin or FSH. Both hormones increased the secretion of plasminogen activator into the culture medium. Relaxin caused a dose-related rise in plasminogen activator but did not increase cAMP or progesterone levels in the medium of freshly harvested granulosa cells, although they were responsive to FSH. This ability of relaxin to stimulate plasminogen activator synthesis without progesterone or cAMP rises indicates that the pathways of post-receptor events leading to stimulation of plasminogen activator differ markedly from those of the gonadotropins. Relaxin is thus a fully characterized peptide hormone produced by the ovary with a well-defined action upon the granulosa cell and may have an intraovarian role in the events leading to ovulation.[1]


  1. Relaxin stimulates plasminogen activator secretion by rat granulosa cells in vitro. Too, C.K., Weiss, T.J., Bryant-Greenwood, G.D. Endocrinology (1982) [Pubmed]
WikiGenes - Universities